We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Read More
9
Vitamin B6 aids heart recovery
Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice.
We explored the potential of vitamin B6 (VB6) in promoting recovery after heart attacks, specifically its role in angiogenesis, which is the formation of new blood vessels. The study aimed to determine whether VB6 could help prevent cardiac dysfunction following acute myocardial infarction (AMI).
To assess the effects of VB6, we conducted both in vitro experiments, examining endothelial cell behavior, and in vivo tests using mice with heart attacks. We discovered that VB6 significantly enhanced cell migration and tubule formation in human umbilical vein endothelial cells, which are critical for blood vessel formation. This process was linked to increased activity of a protein called AMP-activated protein kinase (AMPK).
Interestingly, our findings showed that these beneficial effects of VB6 were reversed when we introduced AMPK inhibitors. This leads us to conclude that VB6 promotes heart recovery by activating AMPK, which in turn supports angiogenesis following AMI. In practical terms, long-term VB6 supplementation after heart attacks led to improved heart function and increased new blood vessel formation in mice, making this vitamin a promising candidate for heart recovery therapies.
Read More
9
Pyridoxamine improves post-MI outcomes
Pyridoxamine improves survival and limits cardiac dysfunction after MI.
We investigated the potential of pyridoxamine, a form of vitamin B6, to improve outcomes after a heart attack (myocardial infarction, or MI). In our study, we divided rats into three groups: one that suffered from MI, another that also received pyridoxamine, and a sham group for comparison.
Over the course of eight weeks, we observed how these treatments impacted heart function using echocardiography and hemodynamic assessments. Remarkably, we found that pyridoxamine not only enhanced survival rates post-heart attack but also significantly reduced harmful levels of advanced glycation end products (AGEs) – compounds that can lead to heart failure.
Specifically, rats treated with pyridoxamine exhibited lower left ventricular pressures and improved heart deformation parameters compared to untreated rats. This better heart function was linked to a decrease in collagen in heart tissue, especially around the damaged area, which is crucial because excess collagen can worsen heart stiffness.
Overall, our findings suggest that pyridoxamine could be a promising therapy for preventing detrimental heart changes following a heart attack, highlighting the value of targeting AGEs in treatment strategies.
Read More
Most Useful Reviews
9
Good heart support
3 people found this helpful
A great heart support and a good substitute for the products at our pharmacy. I am pleased that it lasts a long time!
Read More
8
Tangible heart effect
3 people found this helpful
Magnesium is essential for the normal operation of the heart. Before purchasing domestic magnesium, I tested various brands, and Evalar seemed effective. This magnesium provided an immediate and tangible effect, stabilising my condition with VSD and normalising my heart activity. I take a couple of tablets daily with food, and since there are many in the container, I believe they will last long.
Read More
9
Improved sleep quality
I ordered magnesium from Solgar around 2.5 months ago for ongoing sleep disorders. Initially, there was no noticeable effect, but after a month, the lump in my throat started to ease, and my sleep improved. I managed to control my panic attacks better. While magnesium isn’t a cure-all, it’s a significant step towards comfort and stability. After some time, I realised that my neurological issues were subsiding, which was a relief. Though Solgar's magnesium B6 was pricier, I trust their products more than others.
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Read More
9
Magnesium scaffolds improve heart attack outcomes
Outcomes of the two generations of bioresorbable scaffolds (Magmaris vs. Absorb) in acute coronary syndrome in routine clinical practice.
We examined the performance of two types of bioresorbable scaffolds in patients experiencing acute coronary syndrome (ACS) - a common and serious manifestation of heart disease. Specifically, we compared the effectiveness of magnesium-based scaffolds, known as Magmaris, with the earlier polymer scaffolds called Absorb.
Our study included 193 patients using Magmaris and 160 patients using Absorb, all treated in similar clinical settings. Over the course of one year, we monitored their health outcomes, particularly focusing on serious issues like cardiac death, heart attacks, and instances of scaffold thrombosis.
Surprisingly, we found that patients with Magmaris had significantly better outcomes than those with Absorb. Specifically, the rates of primary complications and target lesion failures were notably lower with Magmaris. We noted a concerning trend with Absorb, where patients experienced a higher rate of scaffold thrombosis.
Overall, our findings suggest that magnesium-based scaffolds could provide a safer and more effective option for patients undergoing treatment for heart attacks compared to their polymer counterparts.
Read More
9
Vitamin B6 aids heart recovery
Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice.
We explored the potential of vitamin B6 (VB6) in promoting recovery after heart attacks, specifically its role in angiogenesis, which is the formation of new blood vessels. The study aimed to determine whether VB6 could help prevent cardiac dysfunction following acute myocardial infarction (AMI).
To assess the effects of VB6, we conducted both in vitro experiments, examining endothelial cell behavior, and in vivo tests using mice with heart attacks. We discovered that VB6 significantly enhanced cell migration and tubule formation in human umbilical vein endothelial cells, which are critical for blood vessel formation. This process was linked to increased activity of a protein called AMP-activated protein kinase (AMPK).
Interestingly, our findings showed that these beneficial effects of VB6 were reversed when we introduced AMPK inhibitors. This leads us to conclude that VB6 promotes heart recovery by activating AMPK, which in turn supports angiogenesis following AMI. In practical terms, long-term VB6 supplementation after heart attacks led to improved heart function and increased new blood vessel formation in mice, making this vitamin a promising candidate for heart recovery therapies.
Read More
9
Pyridoxamine improves post-MI outcomes
Pyridoxamine improves survival and limits cardiac dysfunction after MI.
We investigated the potential of pyridoxamine, a form of vitamin B6, to improve outcomes after a heart attack (myocardial infarction, or MI). In our study, we divided rats into three groups: one that suffered from MI, another that also received pyridoxamine, and a sham group for comparison.
Over the course of eight weeks, we observed how these treatments impacted heart function using echocardiography and hemodynamic assessments. Remarkably, we found that pyridoxamine not only enhanced survival rates post-heart attack but also significantly reduced harmful levels of advanced glycation end products (AGEs) – compounds that can lead to heart failure.
Specifically, rats treated with pyridoxamine exhibited lower left ventricular pressures and improved heart deformation parameters compared to untreated rats. This better heart function was linked to a decrease in collagen in heart tissue, especially around the damaged area, which is crucial because excess collagen can worsen heart stiffness.
Overall, our findings suggest that pyridoxamine could be a promising therapy for preventing detrimental heart changes following a heart attack, highlighting the value of targeting AGEs in treatment strategies.
Read More
8
Magnesium enhances heart attack recovery
Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair.
We explored an innovative approach to treating myocardial infarction (MI) by using a special composite hydrogel that incorporates magnesium-modified black phosphorus nanosheets. This treatment aims to address the significant changes in the heart's environment after a heart attack, which are usually detrimental to recovery.
The research involved creating a hydrogel scaffold that allows for the gradual release of these magnesium-enhanced nanosheets directly at the site of the infarct. This is particularly important because sustained release helps to manage oxidative stress and inflammation, both common issues following a heart attack.
We observed that the black phosphorus nanosheets have a high reactivity with reactive oxygen species (ROS), which helps reduce oxidative stress and inflammation in the heart. Additionally, the magnesium contributes to promoting blood vessel growth, or angiogenesis, which is crucial for long-term heart function after an MI.
Overall, the findings of this study suggest that the combination of these elements in the hydrogel can effectively block further damage from the heart attack and improve recovery outcomes, signaling a promising avenue for heart attack treatments in the future.
A great heart support and a good substitute for the products at our pharmacy. I am pleased that it lasts a long time!
Read More
8
Tangible heart effect
3 people found this helpful
Magnesium is essential for the normal operation of the heart. Before purchasing domestic magnesium, I tested various brands, and Evalar seemed effective. This magnesium provided an immediate and tangible effect, stabilising my condition with VSD and normalising my heart activity. I take a couple of tablets daily with food, and since there are many in the container, I believe they will last long.
Read More
9
Improved sleep quality
I ordered magnesium from Solgar around 2.5 months ago for ongoing sleep disorders. Initially, there was no noticeable effect, but after a month, the lump in my throat started to ease, and my sleep improved. I managed to control my panic attacks better. While magnesium isn’t a cure-all, it’s a significant step towards comfort and stability. After some time, I realised that my neurological issues were subsiding, which was a relief. Though Solgar's magnesium B6 was pricier, I trust their products more than others.
Read More
7.5
Less painful cramps
I took this magnesium during my pregnancy as I was plagued by night cramps. With this supplement, the frequency and pain of my nighttime attacks decreased significantly.
Read More
7.5
Cumulative effects noted
83 people found this helpful
Initially unaware of my magnesium deficiency until advised by my doctor after a troubling cardiogram. I was shocked by the cost but discovered iHerb, where I bought Solgar's Magnesium with B6. The effect isn’t instant but cumulative. I take three tablets daily, and after six months, my heart no longer races, and my general well-being has improved, providing peace for my family and me. I’ve forgotten how to be annoyed over trivial matters, which is a relief.
A heart attack, also known as myocardial infarction, occurs when blood flow to a part of the heart is blocked, often by a blood clot. This interruption can damage or destroy part of the heart muscle, leading to serious health complications or death if not treated promptly. Common symptoms include chest pain, shortness of breath, nausea, and lightheadedness. Risk factors include high blood pressure, high cholesterol, smoking, diabetes, and a sedentary lifestyle.
Preventing a heart attack largely revolves around maintaining a heart-healthy lifestyle. Regular exercise, a balanced diet rich in fruits, vegetables, whole grains, and lean proteins, along with managing stress, can significantly lower the risk. Furthermore, understanding your personal risk factors and engaging with healthcare professionals for regular check-ups can be crucial in both prevention and early detection. If you suspect someone is having a heart attack, it's important to call emergency services immediately, as timely treatment is vital for survival and recovery.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium plays a crucial role in various bodily functions, including heart health. Studies suggest that adequate magnesium levels may help reduce the risk of heart disease and its related conditions. Magnesium is involved in maintaining a normal heartbeat, regulating blood pressure, and supporting the contraction and relaxation of the heart muscle. Additionally, it has been associated with reducing inflammation and oxidative stress, both of which are contributing factors to heart attacks.
However, while some evidence indicates that magnesium supplementation may be beneficial for heart health, it's essential to approach this topic with caution. Magnesium should not be considered a standalone treatment for heart attack prevention or management. It's vital to consult with a healthcare professional before starting any supplementation, especially for individuals with existing heart conditions or those at high risk of heart disease. A balanced diet that includes magnesium-rich foods like leafy greens, nuts, seeds, and whole grains, along with a healthy lifestyle, is typically the most effective strategy for supporting heart health.
Based on user reviews, the time it takes to see results from magnesium supplements, particularly for heart health, varies. For some users, like one who took Solgar's magnesium, the benefits were noticeable after about a month, reporting improved sleep and a reduction in panic attacks Read Review. Others, however, indicated that the effects are not instantaneous but rather cumulative; for instance, one user mentioned significant improvements in their heart condition after about six months of regular intake Read Review.
Additionally, some users experienced rapid relief from discomfort after just a few days of use, showcasing the variable onset of effectiveness Read Review. Overall, while some may find immediate benefits, many users suggest that consistent long-term use (over weeks or months) is often necessary to experience substantial heart health improvements.
Based on recent scientific research, magnesium supplementation suggests a complex but potentially beneficial role in heart attack recovery and outcomes. Studies have revealed that lower magnesium levels correlate with a range of adverse effects, including increased risks of acute kidney injury (AKI), arrhythmias, and even in-hospital mortality among heart attack patients. For instance, one study demonstrated that patients with serum magnesium levels below 1.82 mg/dL had significantly higher rates of complications and mortality compared to those with adequately elevated levels [15]. Furthermore, magnesium's association with improved heart recovery has been explored through innovative treatments, such as magnesium-modified scaffolds that may reduce oxidative stress in the heart following myocardial infarction [4].
However, it is crucial to note that while research highlights the potential benefits of magnesium in heart attack settings, the evidence does not conclusively support magnesium supplementation solely as a treatment method. In fact, some studies stress the importance of monitoring magnesium levels rather than promoting it as a standalone intervention [4]. As we continue to explore the interactions between magnesium and cardiovascular health, further studies are needed to clarify its effectiveness in clinical settings and potential therapeutic applications post-heart attack.
Based on user reviews, several individuals have reported varying improvements in symptoms related to heart health and overall well-being after taking magnesium supplements. For instance, one user noted that Evalar's magnesium provided an "immediate and tangible effect," stabilizing their condition related to VSD and normalizing heart activity (Read Review). Another user, taking Solgar's magnesium, experienced a significant reduction in panic attacks and improvements in sleep and neurological issues after about a month of use (Read Review).
Beyond anxiety and sleep troubles, some users reported relief from physical discomfort. One user recovering from Covid indicated substantial alleviation of heart pain after just a few days of taking a magnesium supplement (Read Review), while another experienced fewer night cramps during pregnancy, attributing the decrease in frequency and pain to the magnesium supplements (Read Review). These anecdotal accounts highlight that while individual results can vary significantly, many users have found magnesium supplements beneficial in managing symptoms related to both heart health and stress management.
Based on user reviews, there are numerous anecdotal accounts highlighting the benefits of combining magnesium supplements with other health practices for managing heart health. One user noted that taking Evalar's magnesium provided immediate stabilization of their condition related to cardiac issues, allowing them to take a couple of tablets daily with food for optimal effect Read Review. Several users, including those who were recovering from Covid or experiencing panic attacks, indicated that supplementing magnesium along with maintaining a regular routine of use contributed significantly to their overall heart health and well-being Read Review.
Furthermore, one specific review pointed out that magnesium has a cumulative effect; after taking Solgar's magnesium with B6 consistently for six months, a user reported marked improvements in heart rate and overall emotional stability Read Review. This suggests that while magnesium can be beneficial on its own, its effectiveness may be enhanced when integrated into a comprehensive health strategy, possibly including dietary considerations and additional lifestyle modifications.
Users report varied dosages of magnesium when using it for heart health, with some finding success in consuming a couple of tablets daily Read Review. Another user mentions taking three tablets daily, highlighting a cumulative effect that improved their heart's condition over six months Read Review. Additionally, a specific magnesium form, Magnesium B6, was noted for its heart-calming benefits, suggesting users consider which formulations might work best for their individual needs Read Review.
Overall, users advocate for magnesium's essential role in heart health; however, responsiveness to the supplement can vary. They advise starting with smaller daily doses and observing effects over time, especially since immediate results are infrequent Read Review. Consulting healthcare professionals to determine appropriate dosages tailored to personal health conditions is also recommended Read Review.
9
Improved sleep quality
I ordered magnesium from Solgar around 2.5 months ago for ongoing sleep disorders. Initially, there was no noticeable effect, but after a month, the lump in my throat started to ease, and my sleep improved. I managed to control my panic attacks better. While magnesium isn’t a cure-all, it’s a significant step towards comfort and stability. After some time, I realised that my neurological issues were subsiding, which was a relief. Though Solgar's magnesium B6 was pricier, I trust their products more than others.
7.5
Cumulative effects noted
83 people found this helpful
Initially unaware of my magnesium deficiency until advised by my doctor after a troubling cardiogram. I was shocked by the cost but discovered iHerb, where I bought Solgar's Magnesium with B6. The effect isn’t instant but cumulative. I take three tablets daily, and after six months, my heart no longer races, and my general well-being has improved, providing peace for my family and me. I’ve forgotten how to be annoyed over trivial matters, which is a relief.
7.5
Heart pain relief
After recovering from Covid, I experienced occasional heart pain. Just a few days of taking this supplement alleviated the discomfort entirely!
8
Tangible heart effect
3 people found this helpful
Magnesium is essential for the normal operation of the heart. Before purchasing domestic magnesium, I tested various brands, and Evalar seemed effective. This magnesium provided an immediate and tangible effect, stabilising my condition with VSD and normalising my heart activity. I take a couple of tablets daily with food, and since there are many in the container, I believe they will last long.
7.5
Less painful cramps
I took this magnesium during my pregnancy as I was plagued by night cramps. With this supplement, the frequency and pain of my nighttime attacks decreased significantly.
6
Surge of strength
I really appreciate Solgar's products due to their high quality. I purchased their magnesium B6, and the characteristics listed were accurate. I've felt a surge of strength, my sleep has improved, and my heart feels calmer now. I highly recommend it!
7.5
Bone and heart health
Magnesium plays a crucial role in strengthening bones, maintaining heart health, and reducing stress. However, it's best not to take it in the form of magnesium oxide.
8
Magnesium levels impact heart attack outcomes
Serum Magnesium Level and It's Relation in Predicting Adverse In-Hospital Outcome in Patients with First Attack of Myocardial Infarction.
We examined whether serum magnesium levels at admission could predict in-hospital outcomes for patients experiencing a heart attack.
In our study of 259 acute myocardial infarction patients, those with lower magnesium levels (below 1.82 mg/dl) faced significantly higher risks of complications, including arrhythmias and even death, compared to those with healthier levels.
Our findings suggest that maintaining adequate magnesium levels is essential for better health outcomes after a heart attack.
7
Magnesium levels and mortality link
Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database.
We investigated how variations in serum magnesium levels might relate to in-hospital mortality for patients experiencing an acute myocardial infarction (AMI), commonly known as a heart attack. The research examined data from over 2,700 patients in intensive care, allowing us to analyze trends over time.
What we found was significant: elevated magnesium levels at ICU admission and changes in magnesium levels within the first 48 hours of ICU stay were associated with a higher risk of in-hospital mortality among these patients. In fact, 18.6% of the patients in our study did not survive their hospital stay.
This relationship remained consistent across different groups, regardless of age, gender, or health severity scores. It highlights the importance of closely monitoring magnesium levels during crucial treatment periods as it may provide insight that could help tailor treatments to improve patient outcomes.
However, we must note that while the study shows an association, it does not isolate the effects of magnesium treatment itself. This means we can't definitively say that magnesium treatment alone drastically alters mortality rates after a heart attack. Instead, the findings suggest magnesium monitoring is vital in intensive care settings.
References
Demirtola Aİ, Mammadli A, Çiçek G. The Role of Magnesium Levels in the Progression of Contrast-Induced Nephropathy in Patients With STEMI Undergoing Primary PCI. Angiology. 2025. 10.1177/00033197251314629
Jin Y, Lin Q, Wang D, Gong M, Huang W, et al. Hypomagnesemia is a Risk Factor for Acute Kidney Injury in Patients Admitted With ST-Segment Elevation Myocardial Infarction: A Retrospective Observational Study. J Ren Nutr. 2024. 10.1053/j.jrn.2024.12.006
Naveen V, Rajesh Lenin R, Stanley LM, Kumar JS. Serum Magnesium Levels and QTc Interval Prolongation As Prognostic Markers in Acute Myocardial Infarction: A Randomized Controlled Study. Cureus. 2024;16:e66051. 10.7759/cureus.66051
Zhuang J, Zhang Q, Wang H, Su PH, Chen PY. Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database. Magnes Res. 2024;37:45. 10.1684/mrh.2024.0517
Zhang J, Sun D, Guo Y, Tong J, Liu Q, et al. Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair. J Nanobiotechnology. 2024;22:433. 10.1186/s12951-024-02685-0
Wang B, Pan S, Nie C, Zou R, Liu J, et al. Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats. Sci Rep. 2024;14:10959. 10.1038/s41598-024-60609-2
Fan C, Qin K, Iroegbu CD, Xiang K, Gong Y, et al. Magnesium lithospermate B enhances the potential of human-induced pluripotent stem cell-derived cardiomyocytes for myocardial repair. Chin Med J (Engl). 2024;137:1857. 10.1097/CM9.0000000000002867
Segev A, Shechter M, Tsur AM, Belkin D, Cohen H, et al. Serum Magnesium Is Associated with Long-Term Survival of Non-ST-Elevation Myocardial Infarction Patients. Nutrients. 2023;15. 10.3390/nu15194299
Włodarczak A, Rola P, Barycki M, Furtan Ł, Łanocha M, et al. Mid-term safety and efficacy of magnesium bioresorbable vascular scaffolds - magmaris in diabetic population. 2-Years outcome in acute coronary syndrome cohort. Diab Vasc Dis Res. 2023;20:14791641231188705. 10.1177/14791641231188705
Sabah Z, Wani J, Deajim M, Al Zomia AS, Asiri A, et al. Serum Magnesium in Patients With Acute Myocardial Infarction and Its Effect on Cardiac Complications and Mortality in Myocardial Infarction Patients. Cureus. 2023;15:e38147. 10.7759/cureus.38147
An P, Wan S, Luo Y, Luo J, Zhang X, et al. Micronutrient Supplementation to Reduce Cardiovascular Risk. J Am Coll Cardiol. 2022;80:2269. 10.1016/j.jacc.2022.09.048
Evers I, Cruijsen E, Kornaat I, Winkels RM, Busstra MC, et al. Dietary magnesium and risk of cardiovascular and all-cause mortality after myocardial infarction: A prospective analysis in the Alpha Omega Cohort. Front Cardiovasc Med. 2022;9:936772. 10.3389/fcvm.2022.936772
Rola P, Włodarczak A, Łanocha M, Barycki M, Szudrowicz M, et al. Outcomes of the two generations of bioresorbable scaffolds (Magmaris vs. Absorb) in acute coronary syndrome in routine clinical practice. Cardiol J. 2022;30:870. 10.5603/CJ.a2022.0047
Ortega-Paz L, Brugaletta S, Gomez-Lara J, Alfonso F, Cequier A, et al. Magnesium-based resorbable scaffold vs permanent metallic sirolimus-eluting stent in patients with ST-segment elevation myocardial infarction: 3-year results of the MAGSTEMI randomised controlled trial. EuroIntervention. 2022;18:e389. 10.4244/EIJ-D-21-00651
Hasan MZ, Nahar K, Sharif JU, Paul SC, Thakur AK, et al. Serum Magnesium Level and It's Relation in Predicting Adverse In-Hospital Outcome in Patients with First Attack of Myocardial Infarction. Mymensingh Med J. 2023;32:65.
Fallesen CO, Antonsen L, Maehara A, Noori M, Hougaard M, et al. Optical Coherence Tomography- Versus Angiography-Guided Magnesium Bioresorbable Scaffold Implantation in NSTEMI Patients. Cardiovasc Revasc Med. 2022;40:101. 10.1016/j.carrev.2021.12.003
Włodarczak A, Łanocha M, Lesiak M, Benett J, Szudrowicz M, et al. Long-term clinical follow-up of the resorbable magnesium scaffolds in acute coronary syndrome patients. Kardiol Pol. 2021;79:827. 10.33963/KP.a2021.0035
Açıkgöz E, Açıkgöz SK, Çiçek G. Serum magnesium concentration may predict no-reflow phenomenon in primary angioplasty for ST-elevation myocardial infarction. Magnes Res. 2020;33:123. 10.1684/mrh.2021.0477
Shlezinger M, Amitai Y, Goldenberg I, Atar S, Shechter M. Acute myocardial infarction severity, complications, and mortality associated with lack of magnesium intake through consumption of desalinated seawater. Magnes Res. 2019;32:39. 10.1684/mrh.2019.0449
Sabaté M, Alfonso F, Cequier A, Romaní S, Bordes P, et al. Magnesium-Based Resorbable Scaffold Versus Permanent Metallic Sirolimus-Eluting Stent in Patients With ST-Segment Elevation Myocardial Infarction: The MAGSTEMI Randomized Clinical Trial. Circulation. 2019;140:1904. 10.1161/CIRCULATIONAHA.119.043467
Ielasi A, Cerrato E, Geraci S, Campo G, Garro N, et al. Sirolimus-Eluting Magnesium Resorbable Scaffold Implantation in Patients with Acute Myocardial Infarction. Cardiology. 2019;142:93. 10.1159/000499536
Lee TM, Chang NC, Lin SZ. Effect of proton pump inhibitors on sympathetic hyperinnervation in infarcted rats: Role of magnesium. PLoS One. 2018;13:e0202979. 10.1371/journal.pone.0202979
de Hemptinne Q, Picard F, Briki R, Awada A, Silance PG, et al. Drug-Eluting Resorbable Magnesium Scaffold Implantation in ST-Segment Elevation Myocardial Infarction: A Pilot Study. J Invasive Cardiol. 2018;30:202.
Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. 10.1016/j.ejphar.2025.177413
Evens L, Beliën H, D'Haese S, Haesen S, Verboven M, et al. Combinational Therapy of Cardiac Atrial Appendage Stem Cells and Pyridoxamine: The Road to Cardiac Repair?. Int J Mol Sci. 2021;22. 10.3390/ijms22179266
Hodzic E. Potential Anti-Inflammatory Treatment of Ischemic Heart Disease. Med Arch. 2018;72:94. 10.5455/medarh.2018.72.94-98
Deluyker D, Ferferieva V, Driesen RB, Verboven M, Lambrichts I, et al. Pyridoxamine improves survival and limits cardiac dysfunction after MI. Sci Rep. 2017;7:16010. 10.1038/s41598-017-16255-y
Ding YP, Pedersen EK, Johansson S, Gregory JF, Ueland PM, et al. B vitamin treatments modify the risk of myocardial infarction associated with a MTHFD1 polymorphism in patients with stable angina pectoris. Nutr Metab Cardiovasc Dis. 2016;26:495. 10.1016/j.numecd.2015.12.009
Myung SK, Ju W, Cho B, Oh SW, Park SM, et al. Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials. BMJ. 2013;346:f10. 10.1136/bmj.f10